Assay Detail
Functional
CHEMBL690652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for blocking of LTD4-induced contractions of guinea pig trachea
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Trachea |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.68 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL162358 | TOMELUKAST | 2.0 | 1 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL162358 | TOMELUKAST | Kd | = | 208.93 | nM | 6.68 |