Assay Detail
Functional
CHEMBL691785
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Antiviral activity determined against herpes simplex virus type 1 (HSV-1) in vero cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
6-Aminoquinolones as new potential anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.38 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL125002 | — | — | 1 | 4.52 |
| CHEMBL123557 | — | — | 1 | 4.48 |
| CHEMBL127498 | — | — | 1 | 4.42 |
| CHEMBL47617 | — | — | 1 | 4.09 |
| CHEMBL124915 | — | — | 1 | - |
| CHEMBL127499 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL125002 | — | EC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL123557 | — | EC50 | = | 33000.0 | nM | 4.48 |
| CHEMBL127498 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL47617 | — | EC50 | = | 82000.0 | nM | 4.09 |
| CHEMBL124915 | — | EC50 | > | 300000.0 | nM | - |
| CHEMBL127499 | — | EC50 | > | 300000.0 | nM | - |