Assay Detail
Functional
CHEMBL692198
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration that stimulated amylase release in guinea pig pancreatic acini relative to CCK-8
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Minor structural differences in Boc-CCK-4 derivatives dictate affinity and selectivity for CCK-A and CCK-B receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.24 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143025 | — | — | 1 | 7.41 |
| CHEMBL3142898 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143025 | — | EC50 | = | 39.0 | nM | 7.41 |
| CHEMBL3142898 | — | EC50 | = | 85.0 | nM | 7.07 |