Assay Detail
Functional
CHEMBL692343
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 was evaluated from schild analyses of the guinea pig ileum contractility data
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and substance P antagonist activity of naphthimidazolium derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.02 | 7.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23682 | — | — | 1 | 7.45 |
| CHEMBL278294 | — | — | 1 | 7.23 |
| CHEMBL386306 | SPANTIDE | — | 1 | 6.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23682 | — | Kd | = | 35.48 | nM | 7.45 |
| CHEMBL278294 | — | Kd | = | 58.88 | nM | 7.23 |
| CHEMBL386306 | SPANTIDE | Kd | = | 426.58 | nM | 6.37 |