Assay Detail
ADMET
CHEMBL693061
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity of compound was determined visually in human diploid fibroblasts (HFF).
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis, antiproliferative, and antiviral activity of certain 4-aminopyrrolo[2,3-d]pyridazine nucleosides: an entry into a novel series of adenosine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.44 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | — | 1 | 6.40 |
| CHEMBL62099 | — | — | 1 | 5.92 |
| CHEMBL611541 | — | — | 1 | 4.00 |
| CHEMBL610706 | — | — | 1 | - |
| CHEMBL603718 | — | — | 1 | - |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | - |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267099 | TUBERCIDIN | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL62099 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL611541 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL610706 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL603718 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL182 | GANCICLOVIR | IC50 | > | 100000.0 | nM | - |
| CHEMBL184 | ACYCLOVIR | IC50 | > | 100000.0 | nM | - |