Assay Detail
Functional
CHEMBL696085
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of ADP induced platelet aggregation in guinea pig
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of an orally active GPIIb/IIIa antagonist based on a phenylpiperazine scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.23 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL36326 | — | — | 1 | 6.60 |
| CHEMBL290497 | — | — | 1 | 6.60 |
| CHEMBL37300 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL36326 | — | IC50 | = | 251.19 | nM | 6.60 |
| CHEMBL290497 | — | IC50 | = | 251.19 | nM | 6.60 |
| CHEMBL37300 | — | IC50 | = | 3162.28 | nM | 5.50 |