Assay Detail
Functional
CHEMBL700465
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In vitro inhibitory activity against human platelet aggregation in the presence of collagen
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Inhibitors of blood platelet aggregation. Effects of some 1,2-benzisothiazol-3-ones on platelet responsiveness to adenosine diphosphate and collagen.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.37 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296312 | — | — | 1 | 4.70 |
| CHEMBL297304 | — | — | 1 | 4.47 |
| CHEMBL417351 | — | — | 1 | 4.24 |
| CHEMBL297639 | — | — | 1 | 4.08 |
| CHEMBL832 | SULFINPYRAZONE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296312 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL297304 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL417351 | — | IC50 | = | 57000.0 | nM | 4.24 |
| CHEMBL297639 | — | IC50 | = | 83000.0 | nM | 4.08 |
| CHEMBL832 | SULFINPYRAZONE | IC50 | > | 1000000.0 | nM | - |