Compound Detail
CHEMBL297639
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL297639 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UOWPTFYGZGEOLW-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
248.3
MW (Da)
2.16
ALogP
4
HBA
0
HBD
25.2
PSA (Ų)
0.83
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Homo sapiens CHEMBL372 | IC50 | 4.52 | 4.3 | 30000.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Homo sapiens | IC50 | = | 30000.0 | nM | 4.52 | The compound was tested ex vivo at a dose of 0.15 mmol/kg for ADP induced platel... | 4067991 |
| Homo sapiens | IC50 | = | 83000.0 | nM | 4.08 | In vitro inhibitory activity against human platelet aggregation in the presence ... | 4067991 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 4067991 | 10.1021/jm00149a021 | Rattus norvegicus | 2 |
| 4067991 | 10.1021/jm00149a021 | Cavia porcellus | 2 |
| 4067991 | 10.1021/jm00149a021 | Homo sapiens | 2 |
Data from ChEMBL 36 via Core Engine