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Assay Detail

CHEMBL700483

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound was tested ex vivo at a dose of 0.15 mmol/kg for ADP induced platelet aggregation in guinea pig
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Inhibitors of blood platelet aggregation. Effects of some 1,2-benzisothiazol-3-ones on platelet responsiveness to adenosine diphosphate and collagen.
Baggaley KH, English PD, Jennings LJ, Morgan B, Nunn B, Tyrrell AW.
J Med Chem (1985) 28 : 1661 -1667
PubMed 4067991 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.52 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL297639 1 4.52
CHEMBL832 SULFINPYRAZONE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL297639 IC50 = 30000.0 nM 4.52
CHEMBL832 SULFINPYRAZONE IC50 = 870000.0 nM -