Assay Detail
Functional
CHEMBL701659
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the growth inhibition of IGROV1 ovarian tumor cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | IGROV-1 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.81 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267616 | — | — | 1 | 6.89 |
| CHEMBL7063 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267616 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL7063 | — | IC50 | = | 190.0 | nM | 6.72 |