IGROV-1 · CELL-LINE · Homo sapiens
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IGROV-1
Review this target as IGROV-1.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats IGROV-1 as ChEMBL target CHEMBL613984. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | IGROV-1 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as IGROV-1.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL96926 | 10.22 | IC50 | 0.0607 | Preclinical |
| CHEMBL888 | 9.84 | IC50 | 0.145 | Approved |
| CHEMBL94657 | 9.81 | IC50 | 0.156 | Clinical |
| CHEMBL2158681 | 9.32 | IC50 | 0.48 | Preclinical |
| CHEMBL150607 | 9.28 | IC50 | 0.52 | Preclinical |
| CHEMBL1834488 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL4214638 | 9.17 | IC50 | 0.68 | Preclinical |
| CHEMBL3628346 | 9.11 | IC50 | 0.77 | Preclinical |
| CHEMBL590740 | 9.01 | IC50 | 0.97 | Preclinical |
| CHEMBL38957 | 9.0 | IC50 | 1.01 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1,134 | 429 | 6.2 |
| organism-based format | 46 | 2 | 6.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 2 | 6.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |