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Assay Detail

CHEMBL710991

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Effect of compound on Melatonin receptor in chicken brain in the presence of MnCl2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Melatonin receptor (CHEMBL2095154)
Type PROTEIN FAMILY
Organism Gallus gallus

Publication

Design and synthesis of new naphthalenic derivatives as ligands for 2-[125I]iodomelatonin binding sites.
Langlois M, Brémont B, Shen S, Poncet A, Andrieux J, Sicsic S, Serraz I, Mathé-Allainmat M, Renard P, Delagrange P.
J Med Chem (1995) 38 : 2050 -2060
PubMed 7783136 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.75 9.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL294517 1 9.75
CHEMBL45 MELATONIN 4.0 1 9.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL294517 Ki = 0.176 nM 9.75
CHEMBL45 MELATONIN Ki = 0.176 nM 9.75