Assay Detail
Functional
CHEMBL714530
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Compound was tested for potency to achieve protection of MT-4 cells from 101E strain of HIV-1 virus
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Evolution of anti-HIV drug candidates. Part 1: From alpha-anilinophenylacetamide (alpha-APA) to imidoyl thiourea (ITU).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.06 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303457 | — | — | 1 | 7.72 |
| CHEMBL37624 | LOVIRIDE | 2.0 | 1 | 7.20 |
| CHEMBL929 | DELAVIRDINE MESYLATE | 4.0 | 1 | 6.80 |
| CHEMBL57 | NEVIRAPINE | 4.0 | 1 | 6.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303457 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL37624 | LOVIRIDE | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL929 | DELAVIRDINE MESYLATE | IC50 | = | 158.0 | nM | 6.80 |
| CHEMBL57 | NEVIRAPINE | IC50 | = | 316.0 | nM | 6.50 |