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Assay Detail

CHEMBL718148

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonist activity in nociception formalin paw seizure model in vivo through ip route; 1-20
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Intermediate

Target

Mus musculus (CHEMBL375)
Type ORGANISM
Organism Mus musculus

Publication

The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
Leeson PD, Iversen LL.
J Med Chem (1994) 37 : 4053 -4067
PubMed 7990104 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289832 LICOSTINEL 2.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289832 LICOSTINEL EC50 = 1000.0 nM 6.00