Assay Detail
Functional
CHEMBL719090
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for the agonistic activity against Metabotropic glutamate receptor 1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Metabotropic glutamate receptor 1 (CHEMBL4477) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC-an apparent mGluR6 selective ligand
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.19 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34453 | — | — | 1 | 4.38 |
| CHEMBL40086 | — | — | 1 | 4.00 |
| CHEMBL60238 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34453 | — | EC50 | = | 42000.0 | nM | 4.38 |
| CHEMBL40086 | — | EC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL60238 | — | EC50 | > | 1000000.0 | nM | - |