Assay Detail
Functional
CHEMBL725633
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Compound was evaluated for IL 5 production inhibition from mice splenocytes stimulated by anti-CD3 mAb
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.50 | 6.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL157424 | — | — | 1 | 6.03 |
| CHEMBL160259 | — | — | 1 | 5.82 |
| CHEMBL348414 | — | — | 1 | 5.64 |
| CHEMBL296419 | ASTEMIZOLE | 4.0 | 1 | 5.48 |
| CHEMBL160617 | — | — | 1 | 5.34 |
| CHEMBL160757 | — | — | 1 | 5.10 |
| CHEMBL158619 | — | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL157424 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL160259 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL348414 | — | IC50 | = | 2280.0 | nM | 5.64 |
| CHEMBL296419 | ASTEMIZOLE | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL160617 | — | IC50 | = | 4560.0 | nM | 5.34 |
| CHEMBL160757 | — | IC50 | = | 7870.0 | nM | 5.10 |
| CHEMBL158619 | — | IC50 | = | 8800.0 | nM | 5.06 |