Assay Detail
Functional
CHEMBL735760
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Tested for potency towards inhibition of the twitch response in mouse vas deferens
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.23 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL120526 | METHANANDAMIDE | — | 1 | 7.92 |
| CHEMBL330974 | — | — | 1 | 7.33 |
| CHEMBL15848 | ANANDAMIDE | — | 1 | 7.28 |
| CHEMBL346659 | — | — | 1 | 7.00 |
| CHEMBL348466 | — | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL120526 | METHANANDAMIDE | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL330974 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL15848 | ANANDAMIDE | IC50 | = | 52.0 | nM | 7.28 |
| CHEMBL346659 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL348466 | — | IC50 | = | 230.0 | nM | 6.64 |