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Assay Detail

CHEMBL737756

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was measured for its inhibitory activity on IFN-gamma-induced nitric oxide production in mouse macrophage
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Intermediate

Target

Mus musculus (CHEMBL375)
Type ORGANISM
Organism Mus musculus

Publication

New enone derivatives of oleanolic acid and ursolic acid as inhibitors of nitric oxide production in mouse macrophages
Honda T, Finlay HJ, Gribble GW, Suh N, Sporn MB
Bioorg Med Chem Lett (1997) 7 : 1623 -1628
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL389621 HYDROCORTISONE 4.0 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL389621 HYDROCORTISONE IC50 = 15.0 nM 7.82