Assay Detail
Functional
CHEMBL738333
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Agonist activity measured on mouse vas deferens (MVD)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Importance of C-6 chirality in conferring irreversible opioid antagonism to naltrexone-derived affinity labels.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.46 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473136 | — | — | 1 | 7.46 |
| CHEMBL21368 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473136 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL21368 | — | IC50 | > | 1000.0 | nM | - |