Assay Detail
Functional
CHEMBL739451
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for immunosuppressive activity which was measured in the mouse mixed lymphocyte reaction
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Isoxazolylthioamides as potential immunosuppressants a combinatorial chemistry approach.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.90 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL999 | — | — | 1 | 5.00 |
| CHEMBL960 | LEFLUNOMIDE | 4.0 | 1 | 5.00 |
| CHEMBL70544 | — | — | 1 | 4.96 |
| CHEMBL69131 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL999 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL960 | LEFLUNOMIDE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL70544 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL69131 | — | IC50 | = | 23000.0 | nM | 4.64 |