Assay Detail
Functional
CHEMBL740146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of the accumulation of (-)-[3H]-5-HT in slices from the middle part of the mouse brain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Homoallylic amines related to zimeldine. A comparative study on neuronal serotonin and norepinephrine reuptake based on conformational analysis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.77 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL37744 | ZIMELDINE | 4.0 | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL37744 | ZIMELDINE | IC50 | = | 1700.0 | nM | 5.77 |