Assay Detail
Functional
CHEMBL740205
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potency in displacing [3H]propionyl-CCK-8 from mouse brain membranes.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activity of CCK26-33-related analogues modified in position 31.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.89 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL384035 | — | — | 1 | 9.89 |
| CHEMBL264597 | — | — | 1 | 8.43 |
| CHEMBL409220 | — | — | 1 | 7.85 |
| CHEMBL410230 | — | — | 1 | 6.96 |
| CHEMBL409963 | — | — | 1 | 6.31 |
| CHEMBL409961 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL384035 | — | Ki | = | 0.13 | nM | 9.89 |
| CHEMBL264597 | — | Ki | = | 3.7 | nM | 8.43 |
| CHEMBL409220 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL410230 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL409963 | — | Ki | = | 490.0 | nM | 6.31 |
| CHEMBL409961 | — | Ki | > | 10000.0 | nM | - |