Assay Detail
Functional
CHEMBL740971
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for inhibiting electrically stimulated muscle contractions in mouse vas deferens (MVD)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Muscle tissue |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Solid phase synthesis of C-terminal carbohydrate modified enkephalins
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.01 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2369528 | — | — | 1 | 8.10 |
| CHEMBL2369514 | — | — | 1 | 7.16 |
| CHEMBL2369513 | — | — | 1 | 6.96 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | — | 1 | 6.55 |
| CHEMBL307868 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2369528 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL2369514 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL2369513 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL35838 | [LEU5]ENKEPHALIN | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL307868 | — | IC50 | = | 550.0 | nM | 6.26 |