Assay Detail
Functional
CHEMBL741189
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for the binding affinity by displacing [3H]oxotremorine from mouse cerebral cortex tissue.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Cerebral cortex |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.29 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 6.66 |
| CHEMBL12937 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL12937 | — | Ki | = | 1200.0 | nM | 5.92 |