Assay Detail
Functional
CHEMBL742914
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Inhibitory concentration of compound was measured in mouse vas deferens assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
[2',6'-Dimethyltyrosine]dynorphin A(1-11)-NH2 analogues lacking an N-terminal amino group: potent and selective kappa opioid antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.82 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL436911 | — | — | 1 | 9.42 |
| CHEMBL216640 | — | — | 1 | 7.89 |
| CHEMBL216899 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL436911 | — | IC50 | = | 0.377 | nM | 9.42 |
| CHEMBL216640 | — | IC50 | = | 12.9 | nM | 7.89 |
| CHEMBL216899 | — | IC50 | = | 722.0 | nM | 6.14 |