Assay Detail
Functional
CHEMBL745592
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity in mouse vas deferens preparation.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.53 | 9.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL340032 | DADLE | — | 1 | 9.66 |
| CHEMBL27465 | — | — | 1 | 7.33 |
| CHEMBL70 | MORPHINE | 4.0 | 1 | 6.61 |
| CHEMBL29772 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL340032 | DADLE | IC50 | = | 0.22 | nM | 9.66 |
| CHEMBL27465 | — | IC50 | = | 47.0 | nM | 7.33 |
| CHEMBL70 | MORPHINE | IC50 | = | 244.0 | nM | 6.61 |
| CHEMBL29772 | — | IC50 | = | 300.0 | nM | 6.52 |