Assay Detail
Functional
CHEMBL746162
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Dissociation constant [1000(nM)] in mouse isolated vas deferens using the cannabinoid receptor agonist.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.73 | 6.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL424527 | — | — | 1 | 6.93 |
| CHEMBL352460 | — | — | 1 | 6.76 |
| CHEMBL422034 | — | — | 1 | 6.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL424527 | — | Kd | = | 118.0 | nM | 6.93 |
| CHEMBL352460 | — | Kd | = | 172.0 | nM | 6.76 |
| CHEMBL422034 | — | Kd | = | 325.0 | nM | 6.49 |