Assay Detail
Functional
CHEMBL746598
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Inhibitory activity before protection from beta-CNS-induced inactivation in MVD
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Investigation of the structural parameters involved in the mu and delta opioid receptor discrimination of linear enkephalin-related peptides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.77 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127378 | — | — | 1 | 9.89 |
| CHEMBL124283 | — | — | 1 | 9.42 |
| CHEMBL38874 | DAMGO | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127378 | — | IC50 | = | 0.13 | nM | 9.89 |
| CHEMBL124283 | — | IC50 | = | 0.38 | nM | 9.42 |
| CHEMBL38874 | DAMGO | IC50 | = | 100.0 | nM | 7.00 |