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Assay Detail

CHEMBL748202

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro binding affinity against guinea pig ileum using [3H]N-methylscopolamine
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Muscarinic acetylcholine receptor M3 (CHEMBL5498)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates.
Kiesewetter DO, Silverton JV, Eckelman WC.
J Med Chem (1995) 38 : 1711 -1719
PubMed 7752195 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.33 8.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL12980 QUINUCLIDINYL BENZILATE 1 8.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL12980 QUINUCLIDINYL BENZILATE Ki = 4.63 nM 8.33