Assay Detail
Binding
CHEMBL748225
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro binding affinity against rat heart membrane using [3H]-AF-DX-384
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Heart |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Muscarinic acetylcholine receptor M2 (CHEMBL309) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Syntheses and biological properties of chiral fluoroalkyl quinuclidinyl benzilates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.74 | 9.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12980 | QUINUCLIDINYL BENZILATE | — | 1 | 9.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12980 | QUINUCLIDINYL BENZILATE | Ki | = | 0.18 | nM | 9.74 |