Assay Detail
Functional
CHEMBL748281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required for stimulation of phosphoinositide hydrolysis in A9L cells expressing human m1 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | A9L |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic m1 receptor activation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 9.70 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL100147 | — | — | 1 | 9.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL100147 | — | EC50 | = | 0.2 | nM | 9.70 |