Assay Detail
Functional
CHEMBL748350
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of mouse submaxillary renin.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.27 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2028991 | — | — | 1 | 8.68 |
| CHEMBL269752 | — | — | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2028991 | — | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL269752 | — | Ki | = | 14.0 | nM | 7.85 |