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Assay Detail

CHEMBL748360

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M2) in Rat Heart
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Muscarinic acetylcholine receptor M2 (CHEMBL309)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Design, synthesis and biological activity of some 4-DAMP- related compounds
Tumiatti V, Santi S, Recanatini M, Minarini A, Melchiorre C, Chiarini A, Budriesi R
Bioorg Med Chem Lett (1995) 5 : 2325 -2330
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL292857 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL292857 Ki = 12.02 nM 7.92