Assay Detail
Binding
CHEMBL749674
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Binding affinity towards human NR2B receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Glutamate receptor ionotropic, NMDA 2B (CHEMBL1904) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Orally efficacious NR2B-selective NMDA receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.02 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL158737 | — | — | 1 | 9.00 |
| CHEMBL49623 | (R,S)-IFENPRODIL | — | 1 | 7.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL158737 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL49623 | (R,S)-IFENPRODIL | Kd | = | 94.0 | nM | 7.03 |