Assay Detail
Functional
CHEMBL749961
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.80 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL146032 | LONAPRISAN | 2.0 | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL146032 | LONAPRISAN | IC50 | = | 16.0 | nM | 7.80 |