Glucocorticoid receptor · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P06537. Use UniProt P06537 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06537 as the stable identity anchor, then attach disease evidence before program review.
Glucocorticoid receptor
Review this target as Glucocorticoid receptor, mapped to UniProt P06537. Sequence length is 792 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glucocorticoid receptor as ChEMBL target CHEMBL3144, mapped to UniProt P06537. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glucocorticoid receptor |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P06537 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glucocorticoid receptor |
| UniProt Accession | P06537 |
| Component Type | Protein |
| Sequence Length | 792 aa |
Glucocorticoid receptor
Review this target as Glucocorticoid receptor, mapped to UniProt P06537. Sequence length is 792 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1276308 | 8.66 | IC50 | 2.2 | Approved |
| CHEMBL372684 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL131 | 8.47 | EC50 | 3.4 | Approved |
| CHEMBL82546 | 8.43 | EC50 | 3.7 | Preclinical |
| CHEMBL364015 | 8.3 | EC50 | 5.0 | Preclinical |
| CHEMBL310570 | 8.28 | EC50 | 5.2 | Preclinical |
| CHEMBL3273976 | 8.12 | Kd | 7.5 | Preclinical |
| CHEMBL362914 | 7.92 | EC50 | 12.0 | Preclinical |
| CHEMBL313062 | 7.82 | EC50 | 15.0 | Preclinical |
| CHEMBL146032 | 7.8 | IC50 | 16.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 18 | 20 | 7.5 |
| organism-based format | 5 | 0 | — |
| single protein format | 3 | 0 | — |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 2 | 8.2 |