Assay Detail
Binding
CHEMBL751672
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Affinity was assessed using competitive binding assay labeled with [3H]DPDPE (6.3 nM) for Opioid receptor delta 1
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Helix-inducing alpha-aminoisobutyric acid in opioid mimetic deltorphin C analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.73 | 9.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86765 | — | — | 1 | 9.96 |
| CHEMBL315225 | — | — | 1 | 9.92 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 9.82 |
| CHEMBL420606 | — | — | 1 | 9.70 |
| CHEMBL315603 | — | — | 1 | 9.10 |
| CHEMBL441889 | — | — | 1 | 8.44 |
| CHEMBL315256 | — | — | 1 | 8.24 |
| CHEMBL83007 | — | — | 1 | 7.81 |
| CHEMBL2370048 | — | — | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86765 | — | Ki | = | 0.11 | nM | 9.96 |
| CHEMBL315225 | — | Ki | = | 0.12 | nM | 9.92 |
| CHEMBL317956 | DELTORPHIN C | Ki | = | 0.15 | nM | 9.82 |
| CHEMBL420606 | — | Ki | = | 0.2 | nM | 9.70 |
| CHEMBL315603 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL441889 | — | Ki | = | 3.62 | nM | 8.44 |
| CHEMBL315256 | — | Ki | = | 5.72 | nM | 8.24 |
| CHEMBL83007 | — | Ki | = | 15.5 | nM | 7.81 |
| CHEMBL2370048 | — | Ki | = | 2628.0 | nM | 5.58 |