Assay Detail
Binding
CHEMBL753005
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Effective concentration against NR1/NR2A receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Ligands for glutamate receptors: design and therapeutic prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.11 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90564 | MIDAFOTEL | 2.0 | 1 | 6.96 |
| CHEMBL84612 | — | — | 1 | 6.55 |
| CHEMBL285123 | (D)-SERINE | 3.0 | 1 | 6.50 |
| CHEMBL773 | GLYCINE | 4.0 | 1 | 6.08 |
| CHEMBL291278 | N-METHYL-D-ASPARTIC ACID (NMDA) | 2.0 | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90564 | MIDAFOTEL | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL84612 | — | EC50 | = | 280.0 | nM | 6.55 |
| CHEMBL285123 | (D)-SERINE | EC50 | = | 320.0 | nM | 6.50 |
| CHEMBL773 | GLYCINE | EC50 | = | 840.0 | nM | 6.08 |
| CHEMBL291278 | N-METHYL-D-ASPARTIC ACID (NMDA) | EC50 | = | 36000.0 | nM | 4.44 |