Assay Detail
Binding
CHEMBL753235
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Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
[Pro(3)]Dyn A(1-11)-NH(2): a dynorphin analogue with high selectivity for the kappa opioid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.30 | 8.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL216640 | — | — | 1 | 8.12 |
| CHEMBL573214 | NORBINALTORPHIMINE | — | 1 | 7.25 |
| CHEMBL405190 | — | — | 1 | 7.17 |
| CHEMBL269377 | — | — | 1 | 5.77 |
| CHEMBL405097 | — | — | 1 | 5.50 |
| CHEMBL407389 | — | — | 1 | 5.24 |
| CHEMBL413729 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL216640 | — | Ki | = | 7.6 | nM | 8.12 |
| CHEMBL573214 | NORBINALTORPHIMINE | Ki | = | 56.0 | nM | 7.25 |
| CHEMBL405190 | — | Ki | = | 67.0 | nM | 7.17 |
| CHEMBL269377 | — | Ki | = | 1700.0 | nM | 5.77 |
| CHEMBL405097 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL407389 | — | Ki | = | 5700.0 | nM | 5.24 |
| CHEMBL413729 | — | Ki | = | 8300.0 | nM | 5.08 |