Assay Detail
Binding
CHEMBL753279
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Compound was tested for binding affinity towards delta-opioid receptor in rat forebrain membrane using [3H]DPDPE
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Forebrain |
| Subcellular | Membrane |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and opioid activity of dynorphin A-(1-13)NH2 analogues containing cis- and trans-4-aminocyclohexanecarboxylic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.66 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL415330 | — | — | 1 | 8.41 |
| CHEMBL2369477 | — | — | 2 | 5.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL415330 | — | Ki | = | 3.88 | nM | 8.41 |
| CHEMBL2369477 | — | Ki | = | 1370.0 | nM | 5.86 |
| CHEMBL2369477 | — | Ki | = | 1910.0 | nM | 5.72 |