Assay Detail
Functional
CHEMBL753302
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Growth inhibitory concentration of compound was measured against murine leukemia cell line (P388)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Preparation of 5-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyloxy)-6-hydroxynap htho[2,3- f]quinoline-7,12-dione (FT-Alz), a new-type, potentially antitumor substance with various biological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.32 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.70 |
| CHEMBL64993 | — | — | 1 | 6.11 |
| CHEMBL65716 | — | — | 1 | 5.16 |
| CHEMBL405065 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL64993 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL65716 | — | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL405065 | — | IC50 | > | 8500.0 | nM | - |