Assay Detail

CHEMBL753314

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Binding

Opioid receptor kappa 1 apparent binding constant from rat brain membranes using [3H]DADLE binding assay

ChEMBL ↗

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Target

Delta-type opioid receptor (CHEMBL269) ↗

Open DB target context

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Delta-type opioid receptor (CHEMBL269) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Delta-type opioid receptor

CHEMBL269

Anchored from Assay target.

Protein identity Delta-type opioid receptor

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

Delta-type opioid receptor (CHEMBL269) ↗

Type	SINGLE PROTEIN
Organism	Rattus norvegicus

Publication

Photoactivatable opiate derivatives as irreversible probes of the mu-opioid receptor.

Galzi JL, Mejean A, Ilien B, Mollereau C, Meunier JC, Goeldner M, Hirth C.
J Med Chem (1990) 33 : 2456 -2464
PubMed 2167979 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.05	8.05

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL290429	CARFENTANIL	2.0	1	8.05

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL290429	CARFENTANIL	Ki	=	9.0	nM	8.05