Assay Detail
Binding
CHEMBL754254
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In vitro inhibitory activity was determined against Opioid receptor delta 1 in mouse vas deferens
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Vas deferens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Enkephalin analogues with 2',6'-dimethylphenylalanine replacing phenylalanine in position 4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.12 | 9.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL100480 | — | — | 1 | 9.77 |
| CHEMBL109327 | — | — | 1 | 8.84 |
| CHEMBL8234 | ENKEPHALIN | — | 1 | 7.65 |
| CHEMBL109554 | — | — | 1 | 6.21 |
| CHEMBL112708 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL100480 | — | IC50 | = | 0.17 | nM | 9.77 |
| CHEMBL109327 | — | IC50 | = | 1.45 | nM | 8.84 |
| CHEMBL8234 | ENKEPHALIN | IC50 | = | 22.2 | nM | 7.65 |
| CHEMBL109554 | — | IC50 | = | 624.0 | nM | 6.21 |
| CHEMBL112708 | — | IC50 | > | 10.0 | nM | - |