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Assay Detail

CHEMBL754471

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of [3H]- ]DSLET binding to Opioid receptor delta 1 from rat brain membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Delta-type opioid receptor (CHEMBL269)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Conformationally restricted deltorphin analogues.
Schiller PW, Weltrowska G, Nguyen TM, Wilkes BC, Chung NN, Lemieux C.
J Med Chem (1992) 35 : 3956 -3961
PubMed 1331451 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.14 8.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL339089 1 8.19
CHEMBL262312 1 8.08

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL339089 Ki = 6.49 nM 8.19
CHEMBL262312 Ki = 8.27 nM 8.08