Assay Detail
Functional
CHEMBL754899
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In vitro cytotoxic activity against mouse leukemia (P388 ) cell line
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structural requirements for biological activity of the marine alkaloid ascididemin
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.22 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL340160 | ASCIDIDEMIN | — | 1 | 6.40 |
| CHEMBL133514 | BENZOSAMPANGINE | — | 1 | 5.80 |
| CHEMBL129860 | — | — | 1 | 4.41 |
| CHEMBL162159 | — | — | 1 | 4.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL340160 | ASCIDIDEMIN | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL133514 | BENZOSAMPANGINE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL129860 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL162159 | — | IC50 | = | 56000.0 | nM | 4.25 |