Assay Detail
Binding
CHEMBL754967
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]- ]DAMGO binding to opioid receptor mu from rat brain membrane
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Conformationally restricted deltorphin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.82 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | — | 1 | 8.03 |
| CHEMBL317956 | DELTORPHIN C | — | 1 | 6.58 |
| CHEMBL124941 | — | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8234 | ENKEPHALIN | Ki | = | 9.43 | nM | 8.03 |
| CHEMBL317956 | DELTORPHIN C | Ki | = | 262.0 | nM | 6.58 |
| CHEMBL124941 | — | Ki | = | 1410.0 | nM | 5.85 |