Assay Detail
Binding
CHEMBL756359
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In vitro binding affinity towards opioid receptor mu 1
45
Total Activities
45
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | unidentified |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
N-alkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, micro and delta opioid agonists: a micro address.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 45 | 7.73 | 9.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63309 | — | — | 1 | 9.85 |
| CHEMBL419621 | — | — | 1 | 9.65 |
| CHEMBL63651 | — | — | 1 | 9.59 |
| CHEMBL68412 | — | — | 1 | 9.18 |
| CHEMBL67289 | — | — | 1 | 9.18 |
| CHEMBL307973 | — | — | 1 | 9.00 |
| CHEMBL67615 | — | — | 1 | 8.80 |
| CHEMBL67240 | — | — | 1 | 8.69 |
| CHEMBL65259 | — | — | 1 | 8.60 |
| CHEMBL67735 | — | — | 1 | 8.52 |
| CHEMBL66741 | — | — | 1 | 8.42 |
| CHEMBL67894 | — | — | 1 | 8.32 |
| CHEMBL67123 | — | — | 1 | 8.21 |
| CHEMBL67790 | — | — | 1 | 8.17 |
| CHEMBL66954 | — | — | 1 | 8.14 |
| CHEMBL63232 | — | — | 1 | 8.06 |
| CHEMBL434018 | — | — | 1 | 8.02 |
| CHEMBL68342 | — | — | 1 | 7.98 |
| CHEMBL67326 | — | — | 1 | 7.87 |
| CHEMBL303875 | — | — | 1 | 7.86 |
| CHEMBL433500 | — | — | 1 | 7.82 |
| CHEMBL291357 | — | — | 1 | 7.77 |
| CHEMBL302142 | — | — | 1 | 7.72 |
| CHEMBL68358 | — | — | 1 | 7.66 |
| CHEMBL303381 | — | — | 1 | 7.66 |
| CHEMBL66955 | — | — | 1 | 7.40 |
| CHEMBL67893 | — | — | 1 | 7.37 |
| CHEMBL67428 | — | — | 1 | 7.28 |
| CHEMBL304214 | — | — | 1 | 7.24 |
| CHEMBL63563 | — | — | 1 | 7.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63309 | — | Ki | = | 0.14 | nM | 9.85 |
| CHEMBL419621 | — | Ki | = | 0.222 | nM | 9.65 |
| CHEMBL63651 | — | Ki | = | 0.26 | nM | 9.59 |
| CHEMBL68412 | — | Ki | = | 0.664 | nM | 9.18 |
| CHEMBL67289 | — | Ki | = | 0.654 | nM | 9.18 |
| CHEMBL307973 | — | Ki | = | 1.01 | nM | 9.00 |
| CHEMBL67615 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL67240 | — | Ki | = | 2.04 | nM | 8.69 |
| CHEMBL65259 | — | Ki | = | 2.52 | nM | 8.60 |
| CHEMBL67735 | — | Ki | = | 2.99 | nM | 8.52 |
| CHEMBL66741 | — | Ki | = | 3.79 | nM | 8.42 |
| CHEMBL67894 | — | Ki | = | 4.8 | nM | 8.32 |
| CHEMBL67123 | — | Ki | = | 6.1 | nM | 8.21 |
| CHEMBL67790 | — | Ki | = | 6.77 | nM | 8.17 |
| CHEMBL66954 | — | Ki | = | 7.16 | nM | 8.14 |
| CHEMBL63232 | — | Ki | = | 8.72 | nM | 8.06 |
| CHEMBL434018 | — | Ki | = | 9.58 | nM | 8.02 |
| CHEMBL68342 | — | Ki | = | 10.52 | nM | 7.98 |
| CHEMBL67326 | — | Ki | = | 13.48 | nM | 7.87 |
| CHEMBL303875 | — | Ki | = | 13.8 | nM | 7.86 |
| CHEMBL433500 | — | Ki | = | 14.98 | nM | 7.82 |
| CHEMBL291357 | — | Ki | = | 17.0 | nM | 7.77 |
| CHEMBL302142 | — | Ki | = | 19.09 | nM | 7.72 |
| CHEMBL303381 | — | Ki | = | 21.7 | nM | 7.66 |
| CHEMBL68358 | — | Ki | = | 21.7 | nM | 7.66 |
| CHEMBL66955 | — | Ki | = | 39.6 | nM | 7.40 |
| CHEMBL67893 | — | Ki | = | 42.46 | nM | 7.37 |
| CHEMBL67428 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL304214 | — | Ki | = | 57.74 | nM | 7.24 |
| CHEMBL63563 | — | Ki | = | 59.0 | nM | 7.23 |
| CHEMBL306463 | — | Ki | = | 61.0 | nM | 7.21 |
| CHEMBL307525 | — | Ki | = | 74.73 | nM | 7.13 |
| CHEMBL292332 | — | Ki | = | 76.0 | nM | 7.12 |
| CHEMBL66800 | — | Ki | = | 84.0 | nM | 7.08 |
| CHEMBL67088 | — | Ki | = | 93.0 | nM | 7.03 |
| CHEMBL64933 | — | Ki | = | 96.0 | nM | 7.02 |
| CHEMBL416680 | — | Ki | = | 101.0 | nM | 7.00 |
| CHEMBL279638 | — | Ki | = | 122.0 | nM | 6.91 |
| CHEMBL67144 | — | Ki | = | 163.0 | nM | 6.79 |
| CHEMBL63912 | — | Ki | = | 265.0 | nM | 6.58 |
| CHEMBL68341 | — | Ki | = | 304.0 | nM | 6.52 |
| CHEMBL68113 | — | Ki | = | 317.0 | nM | 6.50 |
| CHEMBL67781 | — | Ki | = | 608.0 | nM | 6.22 |
| CHEMBL303148 | — | Ki | = | 717.0 | nM | 6.14 |
| CHEMBL304466 | — | Ki | = | 4242.0 | nM | 5.37 |