Assay Detail
Binding
CHEMBL756869
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The binding affinity was measured using [3H]-DIDII against Opioid receptor delta 1 of rat brain
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformationally constrained deltorphin analogs with 2-aminotetralin-2-carboxylic acid in position 3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 9.92 | 10.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL433978 | — | — | 1 | 10.52 |
| CHEMBL369499 | — | — | 1 | 10.46 |
| CHEMBL175116 | — | — | 1 | 10.25 |
| CHEMBL426776 | — | — | 1 | 9.51 |
| CHEMBL433720 | — | — | 1 | 9.41 |
| CHEMBL177647 | — | — | 1 | 9.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL433978 | — | Ki | = | 0.03 | nM | 10.52 |
| CHEMBL369499 | — | Ki | = | 0.035 | nM | 10.46 |
| CHEMBL175116 | — | Ki | = | 0.056 | nM | 10.25 |
| CHEMBL426776 | — | Ki | = | 0.31 | nM | 9.51 |
| CHEMBL433720 | — | Ki | = | 0.385 | nM | 9.41 |
| CHEMBL177647 | — | Ki | = | 0.435 | nM | 9.36 |