Assay Detail
Binding
CHEMBL756870
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The binding affinity was measured using [3H]naltrindole against Opioid receptor delta 1 of rat brain
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Conformationally constrained deltorphin analogs with 2-aminotetralin-2-carboxylic acid in position 3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 9.06 | 10.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL175116 | — | — | 1 | 10.33 |
| CHEMBL369499 | — | — | 1 | 9.29 |
| CHEMBL426776 | — | — | 1 | 9.13 |
| CHEMBL433978 | — | — | 1 | 8.98 |
| CHEMBL177647 | — | — | 1 | 8.40 |
| CHEMBL433720 | — | — | 1 | 8.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL175116 | — | Ki | = | 0.047 | nM | 10.33 |
| CHEMBL369499 | — | Ki | = | 0.515 | nM | 9.29 |
| CHEMBL426776 | — | Ki | = | 0.745 | nM | 9.13 |
| CHEMBL433978 | — | Ki | = | 1.05 | nM | 8.98 |
| CHEMBL177647 | — | Ki | = | 3.95 | nM | 8.40 |
| CHEMBL433720 | — | Ki | = | 5.75 | nM | 8.24 |