Assay Detail
Binding
CHEMBL757139
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory constant for Protein Kinase A
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Target
cAMP-dependent protein kinase A (CHEMBL2111446) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Bos taurus |
Publication
Adenine-arginine mimetics as bisubstrate analog inhibitors of cAMP-dependent protein kinase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.59 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL477 | ADENOSINE | 4.0 | 1 | 4.82 |
| CHEMBL173917 | — | — | 1 | 4.54 |
| CHEMBL173428 | — | — | 1 | 4.42 |
| CHEMBL170701 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL477 | ADENOSINE | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL173917 | — | Ki | = | 29000.0 | nM | 4.54 |
| CHEMBL173428 | — | Ki | = | 38000.0 | nM | 4.42 |
| CHEMBL170701 | — | Ki | = | 150000.0 | nM | - |